.22-250 Rem. Load Data & Reloading Guide
Also known as: .22-250 Remington, .22-250, 5.56×45mm Remington
About .22-250 Rem.
The .22-250 Remington is a high-velocity rifle cartridge that originated in the United States. It was introduced commercially by Remington in 1965 but has roots dating back to the 1930s as a wildcat cartridge based on a necked-down .250-3000 Savage case. Its popularity quickly soared due to its impressive speed and versatility, making it a favorite among varmint hunters and target shooters.
Technically, the .22-250 Remington features a bullet diameter of .224 inches and typically operates with a maximum pressure of about 65,000 psi. It is renowned for its flat trajectory and high muzzle velocities, often exceeding 4,000 feet per second with lighter projectile weights. Common bullet weights for this caliber range from 35 to 55 grains, providing flexibility for a variety of shooting applications.
Ballistically, the .22-250 is appreciated for its significant downrange velocity retention and minimal wind drift, attributes that make it a top choice for varmint hunting over extended distances. The caliber's accuracy and manageable recoil also contribute to its use in precision competitive shooting disciplines. It is particularly effective on small to medium-sized game, such as foxes and coyotes, where high impact velocities ensure clean, humane kills.
For reloaders, the .22-250 Remington offers several advantages. The cartridge responds exceptionally well to careful powder and projectile selection, allowing enthusiasts to fine-tune loads for specific shooting conditions or personal preferences. The abundance of available components and comprehensive data streamline the reloading process. Additionally, the cartridge's flexible case design and durability contribute to an extended service life when properly maintained, making it a cost-effective option for frequent shooters.
Technical Drawing

Technical Specifications
Start Calculating to Develop your own Load Data for .22-250 Rem.
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Start CalculatingBrass Case Capacities
The following table shows the case capacity (Grains of Water) for brass in cartridge .22-250 Rem. where we have data (number of datapoints in brackets).
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Standard Load Data — .22-250 Rem.
Select your desired cartridge and bullet weight below to access the corresponding load table. From there, you can choose any listed load recipe and transfer it directly into the ballistics calculator for further refinement, optimization, and precision tuning.
.224 | 69gr | Sierra MatchKing
.224 | 55gr | Nosler Ballistic Tip Varmint
.224 | 53gr | Hornady V-MAX
.224 | 50gr | Hornady V-MAX
.224 | 65gr | Sierra GameKing
.224 | 50gr | Nosler Ballistic Tip Varmint
.224 | 50gr | Sierra VarmintKing
.224 | 40gr | Nosler Varmageddon
.224 | 55gr | Sierra GameKing
.224 | 50gr | Sierra Tipped VarmintKing
.224 | 60gr | Hornady V-MAX
.224 | 55gr | Nosler Varmageddon
.224 | 55gr | Barnes TTSX BT
.224 | 52gr | Berger Target FB
.224 | 51gr | AERO SB,- smax:9.50
.224 | 50gr | Hornady ECX
.224 | 55gr | Berger Target FB
.224 | 55gr | Hornady S SX
.224 | 74gr | RWS Kegelspitz
.224 | 55gr | Hornady Varmint
.224 | 40gr | Hornady V-MAX
.224 | 35gr | Hornady V-MAX
.224 | 53gr | Sierra MatchKing
.224 | 55gr | Hornady Traditional/FMJ
Community Loads — .22-250 Rem.
Here are some popular loads for .22-250 Rem.:
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| Bullet | Powder | Barrel (in) | Charge (gr) | Case Volume (GoW) | OAL (in) | Max. Pressure (psi) | Muzzle Velocity (fps) | |
|---|---|---|---|---|---|---|---|---|
.224 | 35gr | Hornady V-MAX (35gr) | Vihtav N135 | 24.8 | ••.• | 43.5 | 2.35 | 42,264 (72%) | 3904 | |
.224 | 35gr | Hornady V-MAX (35gr) | Vihtav N135 | 24.8 | ••.• | 43.5 | 2.35 | 36,013 (61%) | 3734 | |
.224 | 35gr | Hornady V-MAX (35gr) | Vihtav N130 | 24.0 | 31.5 | 43.5 | 2.35 | 40,321 (69%) | 3740 | |
.224 | 35gr | Hornady V-MAX (35gr) | Vihtav N130 | 24.8 | 32.0 | 43.5 | 2.35 | 42,206 (72%) | 3819 | |
.224 | 35gr | Hornady V-MAX (35gr) | Vihtav N130 | 24.8 | 33.0 | 43.5 | 2.35 | 46,093 (78%) | 3911 | |
.224 | 36gr | Barnes Varmint Grenade (36gr) | Hodgdo VARGET | 22.0 | ••.• | 43.5 | 2.33 | 52,156 (89%) | 3930 | |
.224 | 36gr | Barnes Varmint Grenade (36gr) | Vihtav N140 | 20.0 | ••.• | 43.5 | 2.35 | 44,918 (76%) | 3665 | |
.224 | 36gr | Barnes Varmint Grenade FB (36gr) | Hodgdo VARGET | 22.0 | ••.• | 43.5 | 2.35 | 51,793 (88%) | 3924 | |
.224 | 40gr | Hornady V-MAX (40gr) | IMR 3031 | 22.0 | ••.• | 43.5 | 2.34 | 52,257 (89%) | 3917 | |
.224 | 40gr | Hornady V-MAX (40gr) | IMR 3031 | 22.0 | ••.• | 43.5 | 2.34 | 52,040 (89%) | 3914 | |
.224 | 40gr | Hornady V-MAX (40gr) | IMR 3031 | 22.0 | ••.• | 43.5 | 2.35 | 52,170 (89%) | 3914 | |
.224 | 40gr | Hornady V-MAX (40gr) | Vihtav N133 | 24.0 | ••.• | 45.5 | 2.40 | 50,502 (86%) | 3819 | |
.224 | 40gr | Hornady V-MAX (40gr) | Hodgdo VARGET | 24.0 | ••.• | 45.5 | 2.40 | 47,674 (81%) | 3819 | |
.224 | 40gr | Hornady V-MAX (40gr) | Hodgdo BL-C2 | 26.0 | ••.• | 43.5 | 2.35 | 43,323 (74%) | 3799 | |
M.224 | 40gr | Hornady V-MAX (40gr) | Norma 201 | 22.0 | ••.• | 43.5 | 2.36 | 53,461 (91%) | 3793 | |
.224 | 40gr | Hornady V-MAX (40gr) | Norma 201 | 22.0 | ••.• | 43.5 | 2.35 | 50,705 (86%) | 3727 | |
.224 | 40gr | Hornady V-MAX (40gr) | Norma 201 | 22.0 | ••.• | 43.5 | 2.36 | 50,459 (86%) | 3724 | |
.224 | 40gr | Hornady V-MAX (40gr) | Vihtav N133 | 24.0 | ••.• | 45.5 | 2.40 | 44,527 (76%) | 3691 | |
.224 | 40gr | Hornady V-MAX (40gr) | Vihtav N135 | 20.0 | ••.• | 43.5 | 2.35 | 48,950 (83%) | 3684 | |
.224 | 40gr | Nosler Varmageddon (40gr) | Hodgdo CFE223 | 22.0 | ••.• | 43.5 | 2.34 | 52,040 (89%) | 3898 | |
.224 | 40gr | Nosler Varmageddon (40gr) | Hodgdo CFE223 | 22.0 | ••.• | 43.5 | 2.35 | 52,214 (89%) | 3898 | |
.224 | 40gr | Nosler Varmageddon (40gr) | Hodgdo CFE223 | 22.0 | ••.• | 43.5 | 2.35 | 52,083 (89%) | 3894 | |
.224 | 40gr | Nosler Varmageddon (40gr) | Hodgdo VARGET | 22.0 | ••.• | 43.5 | 2.35 | 52,228 (89%) | 3812 | |
.224 | 45gr | Hornady Varmint (45gr) | Vihtav N130 | 24.8 | ••.• | 43.5 | 2.35 | 42,380 (72%) | 3501 |
Frequently Asked Questions
The maximum pressure for .22-250 Rem. is 58,740 psi | 4,050 bar.
.22-250 Rem. typically uses a Large Rifle (LR) primer.
The case capacity of .22-250 Rem. is approximately 43.49 grains of water (H₂O).